Bioavailability of pharmaceuticals in Northern Pike in the St. Lawrence River

Bioavailability of pharmaceuticals in Northern Pike in the St. Lawrence River Aquatic systems near major urban centers are constantly contaminated with effluent from wastewater treatment plants (WWTP). Pharmaceuticals are part of the contamination and several classes of drugs have been detected in surface waters in the last decade. To better understand the impact of those pharmaceuticals in ecosystems, the exposure to aquatic species needs to be investigated. This study presents a new simple and rugged quantitative method for the determination of several classes of drugs using plasma from Northern Pike (Esox lucius) environmentally exposed to a major but highly diluted urban effluent. The concentration of six common drugs (diclofenac, ibuprofen, naproxen, salbutamol, sulfamethoxazole and trimethoprim) and one major metabolite (2-hydroxy-ibuprofen) are shown in this dataset. Supplemental Information The St. Lawrence Action Plan (SLAP) 2011 to 2026 (see http://planstlaurent.qc.ca/en/home.html) is the latest Canada-Quebec Agreement on the St. Lawrence and builds on the four previous agreements implemented since 1988. The agreement aims to conserve and enhance the St. Lawrence River. For more information on SLAP, please visit https://www.canada.ca/en/environment-climate-change/services/environmental-funding/ecosystem-initiatives/st-lawrence-action-plan.html 2021-07-29 Environment and Climate Change Canada open-ouvert@tbs-sct.gc.ca Nature and EnvironmentSt. Lawrence RiverÎles de BouchervilleÎlet VertNorthern Pike (Esox lucius)Pharmaceuticalsfishblood plasmaWastewater Treatment Plant (WWTP)St. Lawrence Action Plan (SLAP)Environment SLAP_WWTP_Fish Plasma_Pharmaceuticals EN_FR.csvCSV https://data-donnees.ec.gc.ca/data/substances/monitor/bioavailability-of-pharmaceuticals-in-northern-pike-in-the-st.-lawrence-river/SLAP_WWTP_FishPlasma_Pharmaceuticals_EN_FR.csv View ECCC Data Mart (English)HTML https://data-donnees.ec.gc.ca/data/substances/monitor/bioavailability-of-pharmaceuticals-in-northern-pike-in-the-st.-lawrence-river/ View ECCC Data Mart (French)HTML https://data-donnees.ec.gc.ca/data/substances/monitor/bioavailability-of-pharmaceuticals-in-northern-pike-in-the-st.-lawrence-river/?lang=fr Scientific Publication - Determination of the bioavailability of selected pharmaceutical residues in fish plasma using liquidchromatography coupled to tandem mass spectrometryHTML https://doi.org/10.1016/j.chroma.2017.09.055

Aquatic systems near major urban centers are constantly contaminated with effluent from wastewater treatment plants (WWTP). Pharmaceuticals are part of the contamination and several classes of drugs have been detected in surface waters in the last decade. To better understand the impact of those pharmaceuticals in ecosystems, the exposure to aquatic species needs to be investigated. This study presents a new simple and rugged quantitative method for the determination of several classes of drugs using plasma from Northern Pike (Esox lucius) environmentally exposed to a major but highly diluted urban effluent. The concentration of six common drugs (diclofenac, ibuprofen, naproxen, salbutamol, sulfamethoxazole and trimethoprim) and one major metabolite (2-hydroxy-ibuprofen) are shown in this dataset.

Supplemental Information

The St. Lawrence Action Plan (SLAP) 2011 to 2026 (see http://planstlaurent.qc.ca/en/home.html) is the latest Canada-Quebec Agreement on the St. Lawrence and builds on the four previous agreements implemented since 1988.

The agreement aims to conserve and enhance the St. Lawrence River. For more information on SLAP, please visit https://www.canada.ca/en/environment-climate-change/services/environmental-funding/ecosystem-initiatives/st-lawrence-action-plan.html

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