Summary Safety Review - Loratadine - Abnormal heart rhythm (QT interval prolongation)

Summary Safety Review - Loratadine - Abnormal heart rhythm (QT interval prolongation) Health Canada carried out a safety review to investigate the potential risk of developing an abnormal heart rhythm (QT interval prolongation) with the use of over-the-counter (OTC) drug products containing loratadine. This safety review was triggered by a publication, in the World Health Organization (WHO) Pharmaceuticals NewsletterFootnote1, describing cases of an abnormal heart rhythm (QT interval prolongation) possibly associated with the use of loratadine and desloratadine. 2024-05-09 Health Canada open-ouvert@tbs-sct.gc.ca Health and SafetySummary Safety ReviewLoratadineAbnormal heart rhythmQT interval prolongationuse of over-the-counterdrug products Summary Safety Review - Loratadine - Abnormal heart rhythm (QT interval prolongation)HTML https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada/safety-reviews/summary-safety-review-loratadine-abnormal-heart-rhythm-interval-prolongation.html Summary Safety Review - Loratadine - Abnormal heart rhythm (QT interval prolongation)HTML https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada/safety-reviews/summary-safety-review-loratadine-abnormal-heart-rhythm-interval-prolongation.html Summary Safety Review - Loratadine - Abnormal heart rhythm (QT interval prolongation)HTML https://www.canada.ca/fr/sante-canada/services/medicaments-produits-sante/medeffet-canada/examens-innocuite/resume-examen-innocuite-loratadine-anomalie-rythme-cardiaque-allongement.html

Health Canada carried out a safety review to investigate the potential risk of developing an abnormal heart rhythm (QT interval prolongation) with the use of over-the-counter (OTC) drug products containing loratadine. This safety review was triggered by a publication, in the World Health Organization (WHO) Pharmaceuticals NewsletterFootnote1, describing cases of an abnormal heart rhythm (QT interval prolongation) possibly associated with the use of loratadine and desloratadine.

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